Key result
Higher arterial stiffness was associated with increased odds of orthostatic hypotension, with the highest quartile of pulse wave velocity yielding an OR of 1.45 (95% CI 1.09-1.93) versus the lowest.
Why the study?
Is arterial stiffness associated with orthostatic hypotension in older adults?
Population
3362 elderly men and women aged 55 and older participating in the third examination phase of the Rotterdam…
Comparison
Higher arterial stiffness vs Lower arterial stiffness
Design
Cross-sectional
Authors
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Arterial stiffness may contribute to orthostatic hypotension in older adults; leaves open whether stiffness reduction improves outcomes.
Cross-Sectional (n=3,362)
Is arterial stiffness associated with orthostatic hypotension in older adults?
Odds Ratio: 1.45 (95% CI 1.09–1.93)
Arterial stiffness is independently associated with orthostatic hypotension in older adults, potentially explaining the reduced baroreflex observed with aging.
Mattace‐Raso et al. (2006) conducted a cross-sectional in Orthostatic hypotension (n=3,362). Arterial stiffness (highest quartile of pulse wave velocity) vs. Lowest quartile of pulse wave velocity was evaluated on Orthostatic hypotension (OR 1.45, 95% CI 1.09-1.93). Higher arterial stiffness was associated with increased odds of orthostatic hypotension, with the highest quartile of pulse wave velocity yielding an OR of 1.45 (95% CI 1.09-1.93) versus the lowest.
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