Key result
Orthostatic hypotension (standing systolic BP drop ≥20 mm Hg) in the elderly is associated with altered sympathovagal balance, increased LV wall thickness, and altered LV diastolic filling.
Why the study?
Is orthostatic hypotension associated with impaired left ventricular filling and altered sympathovagal balance in the elderly?
Cohort (n=5,201)
Yes
Is orthostatic hypotension associated with impaired left ventricular filling and altered sympathovagal balance in the elderly?
In the elderly, orthostatic hypotension is associated with altered sympathovagal balance, increased left ventricular wall thickness, and alterations of left ventricular diastolic filling.
No takes yet. Share an insight, caveat, or question.
May flag autonomic-LV interplay in elderly orthostatic hypotension; leaves open causality and intervention effects.
Gottdiener et al. (2000) conducted a cohort in Orthostatic hypotension (n=5,201). Orthostatic hypotension was evaluated on Echocardiographic measures of cardiac structure and function, and autonomic function determined by heart rate variability. Orthostatic hypotension (standing systolic BP drop ≥20 mm Hg) in the elderly is associated with altered sympathovagal balance, increased LV wall thickness, and altered LV diastolic filling.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: