Key result
In patients with Killip class 3 acute myocardial infarction, TIMI thrombus grade ≥ 2 was significantly associated with in-hospital death (OR 5.743), along with older age and lower systolic blood pressure on admission.
Why the study?
Clinical outcomes in acute myocardial infarction patients with Killip class 3 are often inconsistent in the literature, and factors associated with poor outcomes have not been sufficiently investigated.
Cohort (n=205)
No
Odds Ratio: 5.743 (95% CI 1.717–19.214)
p-value: p=0.005
In patients with Killip class 3 acute myocardial infarction, older age, higher coronary thrombus burden, and lower systolic blood pressure on admission are significant predictors of in-hospital mortality.
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Higher thrombus burden may aid risk stratification in Killip class 3 MI; leaves open whether thrombus-targeted interventions improve survival.
Hatori et al. (2021) conducted a cohort in Killip Class 3 Acute Myocardial Infarction (n=205). TIMI thrombus grade ≥ 2 vs. TIMI thrombus grade ≤ 1 was evaluated on In-hospital death (OR 5.743, 95% CI 1.717-19.214, p=0.005). In patients with Killip class 3 acute myocardial infarction, TIMI thrombus grade ≥ 2 was significantly associated with in-hospital death (OR 5.743), along with older age and lower systolic blood pressure on admission.
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