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Four cases of diabetes are reported in which there was no ophthalmoscopic evidence of retinopathy and diabetes remained obscure until fluorescein angiography disclosed signs of retinopathy and multiple microaneurysms. The diagnosis of latent diabetes was made in three of these patients whose fasting blood sugar was normal but the glucose tolerance test was abnormal; in the fourth patient, whose fasting blood sugar and glucose tolerance test were abnormal, the diagnosis of manifest diabetes was made.
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Zetterström et al. (1974) studied this question.
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