Key result
Complete right bundle branch block was associated with significantly worse right ventricular function, including lower RV-fractional area change (P<0.001), compared to incomplete RBBB.
Why the study?
RBBB is independently associated with decreased RV function, a predictor of adverse cardiovascular outcomes, but its effect on RV structure and function in isolated cases required evaluation.
Does complete RBBB compared to incomplete RBBB affect right ventricular structure and function in patients with isolated RBBB?
Cross-Sectional (n=52)
No
Does complete RBBB compared to incomplete RBBB affect right ventricular structure and function in patients with isolated RBBB?
p-value: p=<0.001
Complete RBBB is associated with significantly worse right ventricular systolic function and larger dimensions compared to incomplete RBBB in patients without structural heart disease.
Should not yet change isolated RBBB management; leaves open need for longitudinal RV outcome studies by block subtype.
Background: The prevalence of right bundle branch block (RBBB) is estimated in 0.2 to 1.3% of healthy people. RBBB had independent association with decreased right ventricle (RV) function, which is considered as predictor of adverse cardiovascular outcomes. The aim of this study is to evaluate RV structure and function in patients with isolated RBBB (without structural heart disease) using two-dimensional echocardiography. Methods: A cross-sectional study conducted at Chitwan Medical College, Bharatpur from 1st January 2022 to 30th June 2022. Consecutive adult patients aged ≥18 years with isolated RBBB classified into complete RBBB (CRBBB) and Incomplete RBBB (IRBBB) based on electrocardiographic findings. The echocardiographic evaluation was done to assess RV dimension and function. Results: A total of 52 patients with isolated RBBB were included with mean age of the study population was 45.3 ± 9.3 years, (28 ,53.8%) had CRBBB, whereas the remaining (24, 46.2%) had IRBBB. Among the parameters used to assess RV function; mean RV-Fractional area change (P<0.001), Tricuspid annular plane systolic excursion(P<0.02) and Pulsed Doppler peak velocity at the lateral annulus RV(P<0.001) were significantly lower, while Pulsed Doppler myocardial performance index(P<0.001) was significantly high in CRBBB group as compared to IRBBB group. Similarly, Right atrium and RV dimensional parameters were significant higher in CRBBB compared to IRBBB group. Conclusions: Isolated RBBB is not as benign as it was considered and has deteriorating effect on RV morphology and function. Therefore, patients with Isolated RBBB need follow-up with passing age and more attention toward RV structural and functional analysis.
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Murtuza et al. (2022) conducted a cross-sectional in Isolated right bundle branch block (n=52). Complete right bundle branch block (CRBBB) vs. Incomplete right bundle branch block (IRBBB) was evaluated on Right ventricle structure and function (RV-Fractional area change, TAPSE, peak velocity, myocardial performance index) (p=<0.001). Complete right bundle branch block was associated with significantly worse right ventricular function, including lower RV-fractional area change (P<0.001), compared to incomplete RBBB.
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