Asian race was associated with twofold greater odds of microalbuminuria compared with whites among diabetic patients without hypertension (OR 2.01; 95% CI 1.14-3.53).
Cross-Sectional (n=2,969)
Are there racial and ethnic differences in the prevalence of microalbuminuria and macroalbuminuria among primary care diabetic patients?
Significant racial and ethnic differences exist in the prevalence of early diabetic nephropathy among primary care diabetic patients, which vary by hypertension status, despite comparable healthcare access.
Odds Ratio: 2.01 (95% CI 1.14–3.53)
The objective of this study was to determine whether racial or ethnic differences in prevalence of diabetic microalbuminuria were observed in a large primary care population in which comparable access to health care exists. A cross-sectional analysis of survey and automated laboratory data 2969 primary care diabetic patients of a large regional health maintenance organization was conducted. Study data were analyzed for racial/ethnic differences in microalbuminuria (30 to 300 mg albumin/g creatinine) and macroalbuminuria (>300 mg albumin/g creatinine) prevalence among diabetes registry-identified patients who completed a survey that assessed demographics, diabetes care, and depression. Computerized pharmacy, hospital, and laboratory data were linked to survey data for analysis. Racial/ethnic differences in the odds of microalbuminuria and macroalbuminuria were assessed by unconditional logistic regression, stratified by the presence of hypertension. Among those tested, the unadjusted prevalence of micro- or macroalbuminuria was 30.9%, which was similar among the various racial/ethnic groups. Among those without hypertension, microalbuminuria was twofold greater (odds ratio OR 2.01; 95% confidence interval CI 1.14 to 3.53) and macroalbuminuria was threefold greater (OR 3.17; 95% CI 1.09 to 9.26) for Asians as compared with whites. Among those with hypertension, adjusted odds of microalbuminuria were greater for Hispanics (OR 3.82; 95% CI 1.16 to 12.57) than whites, whereas adjusted odds of macroalbuminuria were threefold greater for blacks (OR 3.32; 95% CI 1.26 to 8.76) than for whites. For most racial/ethnic minorities, hypertriglyceridemia was significantly associated with greater odds of micro- and macroalbuminuria. Among a large primary care population, racial/ethnic differences exist in the adjusted prevalence of microalbuminuria and macroalbuminuria depending on hypertension status. In this setting, racial/ethnic differences in early diabetic nephropathy were observed despite comparable access to diabetes care.
Young et al. (2004) conducted a cross-sectional in Diabetes (n=2,969). Racial/ethnic minority status (Asian, Hispanic, Black) vs. White patients was evaluated on Microalbuminuria and macroalbuminuria prevalence (OR 2.01, 95% CI 1.14-3.53). Asian race was associated with twofold greater odds of microalbuminuria compared with whites among diabetic patients without hypertension (OR 2.01; 95% CI 1.14-3.53).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: