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May 28, 2019World Journal of RadiologyOpen Access

Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging

Keren Bachi Venkatesh Mani Audrey E Kaufman Nadia Alie Rita Z. Goldstein Zahi A. Fayad Nelly Alia‐Klein

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Key Points

This research aims to evaluate inflammation and plaque characteristics in individuals with cocaine use disorder to identify early signs of vascular disease.
Used F-FDG PET imaging to assess vascular inflammation.
Employed 3-D dark-blood MRI to analyze plaque burden, including wall area and thickness.
Assessed drug use severity using standardized instruments.
Majority of individuals with cocaine use disorder showed FDG-PET signals between 1.6 and 3, indicating mild to moderate inflammation.
MRI showed greater wall thickness in cocaine users compared to healthy controls, suggesting increased plaque burden.
Wall area in cocaine users correlated with higher levels of cocaine withdrawal and craving.

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Implication

Assesses plaque inflammation in individuals with cocaine addiction, suggesting early cardiovascular risk detection.

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Cite This Study

Bachi et al. (2019) studied this question.

synapsesocial.com/papers/6a21e898c7675eb28596d8a2 https://doi.org/10.4329/wjr.v11.i5.62

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