Key points are not available for this paper at this time.
Herein, we describe the development of the high-throughput experimentation platform and function in AbbVie's Discovery Chemistry organization. The strategy and approach tailored specifically to medicinal chemistry needs are discussed. Additionally, we disclose the top reaction conditions for the most requested transformations obtained by analysis of the combined data set generated by the platform over five years.
Dombrowski et al. (Thu,) studied this question.