Change in Serum Trace Elements Concentration before and after Removal of Gallbladder with Gallstone

Epidemiological evidence among the human population has shown a significantly increased incidence of gallstone disease worldwide. The levels of nutrients are represented by different physiological and pathological processes. The aim of this work is to analyze the change in trace element (Al, Cd, Cr, Co, Cu, Fe, Pb, Mg, Mn, Ni, Se, and Zn) concentrations of human serum 48h before and after the removal of gallbladder with gallstone in 15 patients by using Inductively Coupled Plasma – Atomic Emission Spectroscopy (ICP-AES). The results showed increased post operative serum Fe, Ni and Se levels and decreased level of other elements significantly. The results were statistically compared (p < 0.05). This study indicates the complexity of interpreting changes in trace elements in serum after surgery.