Key result
Right ventricular apical lead position was independently associated with an increased risk of atrial high rate episodes compared to septal pacing in patients with dual-chamber pacemakers.
Why the study?
The incidence of AHREs and its clinical predictors in Indian patients without a prior history of AF undergoing permanent pacemaker implantation are not well understood.
What is the incidence and what are the clinical predictors of atrial high rate episodes (AHRE) in patients with dual-chamber permanent pacemakers and no prior history of AF?
Cross-Sectional (n=100)
No
What is the incidence and what are the clinical predictors of atrial high rate episodes (AHRE) in patients with dual-chamber permanent pacemakers and no prior history of AF?
In patients with dual-chamber pacemakers and no prior AF, AHREs occurred in 17% over 15 months, with right ventricular apical lead position being a significant independent predictor.
Answers are grounded in this paper and cite their sources.
May support septal over apical RV leads in pacemakers; hypothesis-generating for RCTs on AHRE prevention.
Atrial high rate episodes (AHRE) confers increased morbidity and mortality amongst patients with permanent pacemaker implantation (PPI). The incidence of AHREs and it's clinical predictors in Indian patients without prior history of atrial fibrillation (AF) are not well understood. A total of 100 dual-chamber PPI patients, who had no prior history of AF, underwent pacemaker interrogation starting from a minimum of 1 month after implantation to detect any AHREs. The incidence of AHREs was 17% at a mean follow up 15.2 ± 7.5 months. Only right ventricular apical lead position was found to have an independent association with AHREs (OR: 3.50, 95% CI: 1.02-12.03; p = 0.04).
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Samuel et al. (2022) conducted a cross-sectional in Atrial high rate episodes after dual-chamber permanent pacemaker implantation (n=100). Right ventricular apical lead position vs. Septal lead position was evaluated on Atrial high rate episodes (AHRE) ≥ 5 minutes (OR 3.50, 95% CI 1.02-12.03, p=0.04). Right ventricular apical lead position was independently associated with an increased risk of atrial high rate episodes compared to septal pacing in patients with dual-chamber pacemakers.
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