Key result
Local epicardial strain during quasi-static left ventricular filling was nonuniform, with mean midanterior major and minor extensions of 0-13.9% and 0-7.2%, respectively, at 0-20 mmHg.
This study demonstrates a method for measuring passive ventricular mechanics in isolated dog hearts, revealing nonuniform epicardial strain that challenges mathematical models assuming isotropic myocardial properties.
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Challenges isotropic assumptions in ventricular models; hypothesis-generating for passive mechanics without clinical translation.
McCulloch et al. (1987) studied Isolated arrested dog heart (n=5). Quasi-static left ventricular filling was evaluated on Local epicardial strain. Local epicardial strain during quasi-static left ventricular filling was nonuniform, with mean midanterior major and minor extensions of 0-13.9% and 0-7.2%, respectively, at 0-20 mmHg.
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