Key result
An artificial intelligence-driven screening system for 12-lead ECG images accurately classified exams into Normal, Atrial Fibrillation, and Other with AUROC scores of 93.2%, 99.2%, and 93.1%.
Why the study?
Most ECG classification studies focus on one-dimensional signals, limiting clinical relevance in hospital settings where ECG exams are usually stored as images.
Does an artificial intelligence-driven screening system accurately classify 12-lead ECG images into Normal, Atrial Fibrillation, and Other conditions to prioritize patients in the emergency room?
Observational (n=99,746)
Yes
Does an artificial intelligence-driven screening system accurately classify 12-lead ECG images into Normal, Atrial Fibrillation, and Other conditions to prioritize patients in the emergency room?
Effect estimate: AUROC 99.2% for AFib
A deep learning model can accurately classify 12-lead ECG images into Normal, Atrial Fibrillation, and Other conditions, offering a practical and easily deployable tool for ER triage.
AI ECG image classification supports rapid ER triage prioritization; extends RCT evidence for deep learning in arrhythmia detection.
The electrocardiogram (ECG) serves as a valuable diagnostic tool, providing crucial information about life-threatening cardiac conditions such as atrial fibrillation and myocardial infarction. A prompt and efficient assessment of ECG exams in environments such as Emergency Rooms (ERs) can significantly enhance the chances of survival for high-risk patients. Despite the presence of numerous works on ECG classification, most of these studies have concentrated on one-dimensional ECG signals, which are commonly found in publicly available ECG datasets. Nevertheless, the practical relevance of such methods is limited in hospital settings, where ECG exams are usually stored as images. In this study, we have developed an artificial intelligence-driven screening system specifically designed to analyze 12-lead ECG images. Our proposed method has been trained on an extensive dataset comprising 99,746 12-lead ECG exams collected from the ambulatory section of a tertiary hospital. The primary goal was to precisely classify the exams into three classes: Normal (N), Atrial Fibrillation (AFib), and Other (O). The evaluation of our approach yielded AUROC scores of 93.2%, 99.2%, and 93.1% for N, AFib, and O, respectively. To further validate our approach, we conducted evaluations using the 2018 China Physiological Signal Challenge (CPSC) database. In this evaluation, we achieved AUROC scores of 91.8%, 97.5%, and 70.4% for the classes N, AFib, and O, respectively. Additionally, we assessed our method using 1,074 exams acquired in the ER and obtained AUROC values of 98.3%, 98.0%, and 97.7% for the classes N, AFib, and O, respectively. Furthermore, we developed and deployed a system with a trained model within the ER of a tertiary hospital for research purposes. This system automatically retrieves newly captured ECG chart images from the Picture Archiving and Communication System (PACS) within the ER. These images undergo necessary preprocessing steps and serve as input for our proposed classification method. This comprehensive approach established an efficient and versatile end-to-end framework for ECG classification. The results of our study highlight the potential of leveraging artificial intelligence in the screening of ECG exams, offering a promising solution for the rapid assessment and prioritization of patients in the ER.
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Dias et al. (2023) conducted an observational in Cardiac conditions (n=99,746). Artificial intelligence-driven screening system was evaluated on Classification into Normal, Atrial Fibrillation, and Other (AUROC 99.2% for AFib). An artificial intelligence-driven screening system for 12-lead ECG images accurately classified exams into Normal, Atrial Fibrillation, and Other with AUROC scores of 93.2%, 99.2%, and 93.1%.
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