What is the clinical evidence from this study?

Study design: Observational. Population: Twin-twin transfusion syndrome (TTTS) (n=5). Intervention: Recipient twin status in twin-twin transfusion syndrome. Primary outcome: Increased cardiothoracic ratio and tricuspid regurgitation.

July 1, 1994HeartOpen Access

Clinical and echographic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome.

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Key result

In 5 pregnancies complicated by twin-twin transfusion syndrome, all recipient twins (100%) developed increased cardiothoracic ratio and tricuspid regurgitation in utero.

Population

Twin pregnancies complicated by twin-twin transfusion syndrome with severe polyhydramnios diagnosed earlier…

Design

Case_series

Follow-up

Up to 7 months postnatally

Authors

NZN. ZosmerHarris Birthright Research Centre for Fetal Medicine RBRekha BajoriaInstitute for Reproductive Health EWEhud WeinerEmek Medical Center

Discussion

Member takes

Implication

May warrant enhanced surveillance of recipient twins; leaves open optimal monitoring protocols pending larger studies.

Study Design

Type

Observational (n=5)

Multicenter

Yes

Structured PICO

Population

5 twin pregnancies complicated by TTTS with severe polyhydramnios diagnosed earlier than 25 weeks, followed from the antenatal period to up to 7 months postnatally.

Exposure

Serial fetal echocardiography with colour Doppler, postnatal echocardiography, and serial amnioreduction (with digoxin, pericardiocentesis, paracentesis, or laser ablation for hydrops as needed).

Outcome

Abnormal echocardiographic features and clinical complications of cardiac disease in the recipient twin.surrogate

Recipient twins in TTTS acquire in utero cardiac disease ranging from mild to critical pulmonary stenosis or lethal cardiomyopathy, warranting close postnatal follow-up.

Cite This Study

Zosmer et al. (1994) conducted an observational in Twin-twin transfusion syndrome (TTTS) (n=5). Recipient twin status in twin-twin transfusion syndrome was evaluated on Increased cardiothoracic ratio and tricuspid regurgitation. In 5 pregnancies complicated by twin-twin transfusion syndrome, all recipient twins (100%) developed increased cardiothoracic ratio and tricuspid regurgitation in utero.

synapsesocial.com/papers/6a220aaa1b095894fc4eb85c https://doi.org/10.1136/hrt.72.1.74

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Clinical and echographic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome.

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Clinical and echographic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome.

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider