Answers are grounded in this paper and cite their sources.
Demonstrates improvement of dystonia through deep brain stimulation in a patient, indicating therapeutic potential.
Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in a patient with severe idiopathic generalized dystonia resulted in immediate improvement of all aspects of dystonia. During joystick movement, GPi DBS reduced PET activation bilaterally in the primary motor, lateral premotor, supplementary motor, anterior cingulate, and prefrontal areas and ipsilaterally in the lentiform nucleus. Altering basal ganglia function with GPi DBS reverses the overactivity of certain motor cortical areas present in dystonia.
No takes yet. Share an insight, caveat, or question.
Kumar et al. (1999) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: