Key result
A novel finger arterial stiffness index was significantly correlated with allostatic load (r=0.40), C-reactive protein (r=0.39), and HDL cholesterol (r=-0.36) in healthy young men.
Why the study?
Is a novel finger arterial stiffness index associated with allostatic load and psychosocial stress in healthy young men?
Cross-Sectional (n=37)
Is a novel finger arterial stiffness index associated with allostatic load and psychosocial stress in healthy young men?
A novel finger arterial stiffness index correlates with vascular proinflammation, allostatic load, and psychosocial stress in healthy young men.
May signal early stress-related vascular changes in young men; hypothesis-generating and leaves open prospective validation before clinical use.
A novel index of finger arterial stiffness (FSI) was tested in terms of the relationship with risk markers for preclinical cardiovascular disease. In addition, we examined if the association between psychosocial factors and FSI was explained by allostatic load markers in 37 healthy young men aged 24.8 ± 4.0 years. The FSI was devised based on an exponential model of the finger arterial pressure‐volume relationship. The allostatic load index (ALI) as a cumulative risk marker was defined by the mean of standard scores for nine variables: resting systolic and diastolic blood pressure, waist/hip ratio, high‐density lipoprotein cholesterol (HDL‐C), total cholesterol/HDL‐C ratio, triglycerides, hemoglobin A1c, insulin resistance, and high sensitivity C‐reactive protein (CRP). Partial correlations controlling for age were significant for FSI with HDL‐C ( r = −.36), CRP ( r = .39), ALI ( r = .40), unhealthy overall eating habits ( r = .34), hostility using the Buss‐Perry Aggression Questionnaire ( r = .38), and manageability in Sense of Coherence ( r = −.38). In conclusion, FSI seems to be associated with vascular proinflammation as well as with overall physiological dysregulation and allostatic load. These associations were moderated by eating lifestyle and psychosocial stress.
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Tanaka et al. (2011) conducted a cross-sectional in Healthy (n=37). Psychosocial factors and allostatic load was evaluated on Correlation of finger arterial stiffness index (FSI) with risk markers for preclinical cardiovascular disease and allostatic load (r = 0.40 for ALI). A novel finger arterial stiffness index was significantly correlated with allostatic load (r=0.40), C-reactive protein (r=0.39), and HDL cholesterol (r=-0.36) in healthy young men.
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