Key result
Waist circumference (β=0.11, P=.02), waist-to-hip ratio, and body roundness index were associated with cf-PWV and cAIx, while physical activity was negatively associated with cAIx (β=-0.08, P=.03).
Why the study?
Arterial stiffness indicates early-stage cardiovascular disease associated with modifiable and lifestyle risk factors, prompting evaluation of its association with anthropometric indices, lipid profiles, and physical activity.
Are anthropometric indices, lipid profiles, and physical activity associated with arterial stiffness in healthy middle-aged adults?
Cohort (n=658)
Are anthropometric indices, lipid profiles, and physical activity associated with arterial stiffness in healthy middle-aged adults?
Central obesity indices and lipid profiles are positively associated with arterial stiffness in healthy middle-aged adults, whereas physical activity is inversely associated with central augmentation index.
Central obesity indices may aid risk stratification; hypothesis-generating for interventions, with no practice change warranted yet.
BACKGROUND: Arterial stiffness (AS) indicates the initial stage of cardiovascular disease (CVD), which is associated with modifiable and lifestyle risk factors. We aimed to examine the association of AS with anthropometric indices, lipid profiles and physical activity (PA). METHODS: Six hundred and fifty-eight healthy middle-aged adults were selected and anthropometric indices [body mass index, waist circumferences (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), neck circumferences, a body shape index (ABSI), body roundness index (BRI), body fat mass (BFM), visceral fat area, fat-free mass (FFM), lipid profiles and PA] were measured. AS is measured by carotid-femoral pulse wave velocity (cf-PWV) and central augmentation index (cAIx). RESULTS: Our results show that cf-PWV was positively associated with TGs (β = 0.10, P = .01) and anthropometric indices correlated with WC (β = 0.11, P = .02), WHR (β = 0.09, P = .03), WHtR (β = 0.1, P = .02) and BRI (β = 0.09, P = .04). cAIx was independently positively associated with cholesterol (β = 0.08, P = .03), WC (β = 0.1, P = .03), WHR (β = 0.09, P = .02), ABSI (β = 0.09, P = .01), BRI (β = 0.08, P = .05), visceral fat area (β = 0.09, P = .03) and BFM (β = 0.08, P = .04) and negatively associated with PA (β = -0.08, P = .03). CONCLUSIONS: WC, WHR and BRI were associated with both cf-PWV and cAIx. TGs and WHtR were associated with cf-PWV, while cAIx was associated with ABSI, improving these indices may be helpful to prevent CVD.
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Nosrati‐Oskouie et al. (2021) conducted a cohort in Healthy middle-aged adults (n=658). Anthropometric indices, lipid profiles, and physical activity was evaluated on Arterial stiffness measured by carotid-femoral pulse wave velocity (cf-PWV) and central augmentation index (cAIx). Waist circumference (β=0.11, P=.02), waist-to-hip ratio, and body roundness index were associated with cf-PWV and cAIx, while physical activity was negatively associated with cAIx (β=-0.08, P=.03).
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