What does this research mean for the field?

Emerging anthropometric indices, particularly weight-adjusted waist index (WWI) and visceral adiposity index (VAI), are significantly associated with increased arterial stiffness, while lipid accumulation product (LAP) exhibits a protective association against arterial stiffness in individuals without cardiovascular disease. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to explore the association between emerging anthropometric ratios and arterial stiffness measured by pulse wave velocity.

June 6, 2026Journal of Health Population and NutritionOpen Access

Association of emerging anthropometric ratios with arterial stiffness risk measured by pulse wave velocity: insights from a middle-eastern population

Q: What are the key findings of this study?

Higher weight-adjusted waist index and visceral adiposity index were significantly associated with increased odds of arterial stiffness (OR 1.257; 95% CI 1.002-1.576 and OR 1.139; 95% CI 1.022-1.271).

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Arterial stiffness (n=823). Intervention: Novel anthropometric indices (weight-adjusted waist index, visceral adiposity index) vs. Lower anthropometric indices. Primary outcome: Arterial stiffness (pulse wave velocity ≥ 6.9 m/s) (OR 1.257, 95% CI 1.002-1.576, p=0.048).

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Key result

Higher weight-adjusted waist and visceral adiposity indices link to ~26% higher arterial stiffness odds.

OR 1.257
95% CI 1.002-1.576
P=0.048
n=823

Why the study?

Arterial stiffness is a strong risk factor for atherosclerosis and CAD, motivating an exploration of its relationship with novel anthropometric indices.

Are novel anthropometric indices associated with arterial stiffness measured by pulse wave velocity in a middle-eastern population?

Population

823 participants from the MASHAD cohort study

Comparison

Novel anthropometric indices evaluated against arterial stiffness categorized by median PWV < 6.9 vs ≥ 6.9 m/s

Design

Cross-sectional study

Authors

MIMobina ImannezhadMashhad University of Medical Sciences SDSusan DarroudiUniversity of Modena and Reggio Emilia MSMaryam Saberi-KarimianMashhad University of Medical Sciences

Discussion

Member takes

Implication

Should not yet change arterial stiffness risk assessment; leaves open whether these indices add predictive value in prospective cohorts.

Key Points

This research aims to explore the association between emerging anthropometric ratios and arterial stiffness measured by pulse wave velocity.
Cross-sectional analysis during Phase II of the MASHAD study with 823 participants.
Participants categorized into groups based on pulse wave velocity measurements.
Utilized multinomial logistic regression to analyze associations between anthropometric indices and arterial stiffness.
Weight-adjusted waist index and visceral adiposity index significantly increased arterial stiffness risk (OR: 1.257, P=0.048; OR: 1.139, P=0.019).
Lipid accumulation product was protective against arterial stiffness (OR: 0.996, P=0.01).
Height and arm-to-height ratio also linked to increased risk of arterial stiffness (OR: 1.037, P=0.034; OR: 1.064, P=0.044).

Study Design

Type

Cross-Sectional (n=823)

Multicenter

Structured PICO

Are novel anthropometric indices associated with arterial stiffness measured by pulse wave velocity in a middle-eastern population?

Population

823 participants from a Middle-Eastern cohort, including healthy individuals and those with or without confirmed cardiovascular disease, assessed for arterial stiffness.

Exposure

Novel anthropometric indices including weight-adjusted waist index (WWI), visceral adiposity index (VAI), lipid accumulation product (LAP), and arm-to-height ratio (AHR)

Outcome

Arterial stiffness assessed by pulse wave velocity (PWV) ≥ 6.9 m/ssurrogate

Main Result

Odds Ratio: 1.257 (95% CI 1.002–1.576)

p-value: p=0.048

Novel anthropometric indices, specifically weight-adjusted waist index and visceral adiposity index, are significantly associated with increased arterial stiffness, highlighting their potential utility in cardiovascular risk assessment.

Cite This Study

Imannezhad et al. (2026) conducted a cross-sectional in Arterial stiffness (n=823). Novel anthropometric indices (weight-adjusted waist index, visceral adiposity index) vs. Lower anthropometric indices was evaluated on Arterial stiffness (pulse wave velocity ≥ 6.9 m/s) (OR 1.257, 95% CI 1.002-1.576, p=0.048). Higher weight-adjusted waist index and visceral adiposity index were significantly associated with increased odds of arterial stiffness (OR 1.257; 95% CI 1.002-1.576 and OR 1.139; 95% CI 1.022-1.271).

synapsesocial.com/papers/6a23ba3c71a5da9775e7602e https://doi.org/10.1186/s41043-026-01338-2

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Association of emerging anthropometric ratios with arterial stiffness risk measured by pulse wave velocity: insights from a middle-eastern population

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Association of emerging anthropometric ratios with arterial stiffness risk measured by pulse wave velocity: insights from a middle-eastern population

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider