December 1, 2019Artery ResearchOpen Access

Analysis of Vascular Aging in Arterial Hypertension — Population-based Study: Preliminary Results

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Why the study?

Arterial hypertension is a complex disease with arterial stiffness as a key alteration, and pulse wave velocity is a gold standard marker of vascular aging and cardiovascular risk.

Does arterial hypertension increase arterial stiffness (pulse wave velocity) in a general adult population?

Population

Individuals in the restricted area of Vale do Ogunja, Salvador-Bahia

Comparison

Hypertensive patients vs non-hypertensive individuals

Design

Cross-sectional population-based study

Authors

JCJuan Jailson Oliveira Almeida CostaFaculdade de Tecnologia e Ciências RCRoberta Castro de Araújo CunhaFaculdade de Tecnologia e Ciências AFAntonio de Assis Oliveira Alves FilhoFaculdade de Tecnologia e Ciências

Discussion

Member takes

Implication

Hypertension may warrant arterial stiffness assessment; supports association in adults but leaves open causality and outcomes.

Structured PICO

Does arterial hypertension increase arterial stiffness (pulse wave velocity) in a general adult population?

Population

151 adults (aged ≥18 years) from a population-based sample in Salvador-Bahia, Brazil. Mean age 47.0, 70.2% female. Excluded pregnant women, bedridden individuals, and those with locomotion difficulty.

Intervention

Arterial hypertension (observational exposure)

Comparator

Non-hypertensive (normotensive) individuals

Outcome

Arterial stiffness assessed by Pulse Wave Velocity (PWV ≥ 10 m/s)surrogate

Arterial hypertension is strongly associated with increased arterial stiffness and vascular aging, as measured non-invasively by pulse wave velocity.

Limitations

Cross-sectional design not allowing cause and effect relationship to be established
Preliminary small sample size
Data losses in some variables, particularly PWV measurements in elderly individuals

Cite This Study

Costa et al. (2019) studied this question.

synapsesocial.com/papers/6a10175d5725bbd5cc607d7d https://doi.org/10.2991/artres.k.191201.001

Topics

Hypertension management

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Analysis of Vascular Aging in Arterial Hypertension — Population-based Study: Preliminary Results

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Analysis of Vascular Aging in Arterial Hypertension — Population-based Study: Preliminary Results

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider