Key result
Lower rates of systolic nocturnal blood pressure dipping, advanced age, and low estimated glomerular filtration rate were independently associated with increased arterial stiffness in patients with essential hypertension.
Why the study?
ABPM provides insights into arterial stiffness, but the relationship between aortic pulse wave velocity, 24-hour ABPM, and clinical and laboratory parameters in hypertensive individuals required investigation.
What clinical and laboratory parameters are independently associated with arterial stiffness (measured by PWV) in hypertensive individuals?
Cross-Sectional (n=131)
No
What clinical and laboratory parameters are independently associated with arterial stiffness (measured by PWV) in hypertensive individuals?
Effect estimate: Beta -0.113 (95% CI -0.050 to -0.010)
p-value: p=0.004
Increased arterial stiffness in hypertensive patients is independently associated with advanced age, impaired renal function, and lack of nocturnal systolic dipping.
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These associations in essential hypertension are hypothesis-generating; prospective studies needed before clinical adoption.
Tüfekçı̇ et al. (2023) conducted a cross-sectional in Essential hypertension (n=131). Systolic dipping vs. Lower rates of systolic dipping was evaluated on Pulse wave velocity (PWV) (Beta -0.113, 95% CI -0.050 to -0.010, p=0.004). Lower rates of systolic nocturnal blood pressure dipping, advanced age, and low estimated glomerular filtration rate were independently associated with increased arterial stiffness in patients with essential hypertension.
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