Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study

158 patients undergoing coronary artery bypass graft (CABG) surgery, mean age 64.7 years, 20.9% female, recruited at a single center in Australia.

Preoperative diagnosis of generalized anxiety disorder (GAD), distress disorders, fear disorders, or elevated symptom dimensions (anhedonia, anxious arousal, general negative affect)

Patients without the respective preoperative affective disorders or elevated symptom dimensions

Incident major adverse cardiovascular and cerebrovascular events (MACCE) defined as fatal or non-fatal myocardial infarction, unstable angina pectoris, repeat revascularization, heart failure, sustained arrhythmia, stroke or cerebrovascular accident, left ventricular failure, and mortality due to cardiac causes at median 4.6 years follow-upcomposite