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This research investigates whether Pneumocystis carinii can be transmitted from infected individuals to healthy contacts.

Transmission of Pneumocystis carinii DNA from a Patient with P. carinii Pneumonia to Immunocompetent Contact Health Care Workers

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This research investigates whether Pneumocystis carinii can be transmitted from infected individuals to healthy contacts.
Prospectively obtained noninvasive deep-nasal-swab samples from an infected child and his contacts, including health care workers.
Nested-DNA amplification was used to detect P. carinii specific DNA.
Comparison made with samples from 30 hospital staff members who did not enter the patient's room.
P. carinii f. sp. hominis DNA detected in samples from the patient and all contacts (mother and health care workers).
No P. carinii DNA found in any samples from 30 hospital staff members, indicating selective transmission.
Findings align with previous murine models supporting person-to-person transmission of P. carinii.

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Randomized trial detects P. carinii DNA transmission in health care workers, suggesting precautions for immunocompromised patients.

Vargas et al. (2000) studied this question.

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