Key result
Over two decades, age-adjusted left ventricular mass increased in men (192 g to 198 g, p-trend=0.0005) but decreased in women (147 g to 140 g, p-trend<0.0001).
Cohort (n=4,320)
No
p-value: p-trend=0.0005 (men); p-trend<0.0001 (women)
Over two decades, echocardiographic left ventricular mass showed sex-related differences in trends, with a modest increase in men (likely due to increasing body size) and a decrease in women.
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Sex-specific LV mass trends may inform risk assessment; leaves open mechanisms and outcome implications.
Kaess et al. (2013) conducted a cohort in Community-based cohort (n=4,320). Secular time trends vs. Earlier examination cycles was evaluated on Sex-specific trends in mean LVM (p=p-trend=0.0005 (men); p-trend<0.0001 (women)). Over two decades, age-adjusted left ventricular mass increased in men (192 g to 198 g, p-trend=0.0005) but decreased in women (147 g to 140 g, p-trend<0.0001).
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