Answers are grounded in this paper and cite their sources.
Designers of electron microscopes are often pulled in two directions: a) maximizing the performance, such as the microscope's spatial resolution, energy resolution, beam current, and stability, b) maximizing the flexibility, i.e. the microscope's ability to perform a variety of experiments beyond imaging and diffraction, such as in-situ/operando microscopies, and various spectroscopies.
No takes yet. Share an insight, caveat, or question.
Hotz et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: