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FROM the clinician's practical point of view the wider application of transplantation as a remedy for disease is being restrained by a number of factors. The available supply of organs in an acceptable physiologic state falls short of the demand. The facilities and financing that would allow maintenance of patients in need of organ transplants, particularly kidneys, are still inadequate and poorly coordinated. But the central obstacle is the rejection reaction, which remains an incompletely solved problem. Nevertheless, it is clear that organ transplants can attain productive life for patients previously near death. An operational solution to the problems of . . .
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Russell et al. (1970) studied this question.
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