GLOMERULAR deposits of IgA are common and are thought to play an important part in the pathogenesis of several different diseases. Primary IgA nephropathy (Berger's disease) is a common type of glomerulonephritis that occurs chiefly in early adult life; the patient presents with a history of recurrent episodes of macroscopic or microscopic hematuria. The onset of symptoms has been reported to coincide with or follow soon after an upper-respiratory-tract infection or gastroenteritis. Renal impairment is usually mild, but some patients progress to end-stage renal failure, and the disease tends to recur in grafted kidneys after transplantation.1 Glomerular lesions characterized by . . .
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André et al. (1980) studied this question.
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