The purified Escherichia coli B41 endonuclease for depurinated DNA is strictly specific for apurinic sites; it has no action on DNA normal strands, or on strands carrying alkylated sites. The possible identity of this enzyme with endonuclease II, described as hydrolyzing alkylated and depurinated DNA, is discussed.
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Paquette et al. (1972) studied this question.
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