December 11, 1981Science
Type III Hyperlipoproteinemia Associated with Apolipoprotein E Deficiency
Key result
A new kindred of patients with type III hyperlipoproteinemia was found to have no detectable plasma apolipoprotein E, suggesting the condition may be due to an absence or striking deficiency of apo E.
Population
A kindred of patients with type III hyperlipoproteinemia
Design
Case_series
Authors
Discussion
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Member takes
Implication
May link apo E absence to type III hyperlipoproteinemia; leaves open causality and generalizability beyond this kindred.
Study Design
Type
Case Report
Structured PICO
P
Population
A kindred of patients with type III hyperlipoproteinemia.
O
Outcome
Plasma apolipoprotein E levelssurrogate
Demonstrates that type III hyperlipoproteinemia can be associated with a complete absence of apolipoprotein E.
Cite This Study
Ghiselli et al. (1981) conducted a case report in Type III hyperlipoproteinemia. Apolipoprotein E deficiency was evaluated on Plasma apolipoprotein E levels. A new kindred of patients with type III hyperlipoproteinemia was found to have no detectable plasma apolipoprotein E, suggesting the condition may be due to an absence or striking deficiency of apo E.