Key result
Hemodialysis was associated with a significantly higher risk of hospitalization for atrial fibrillation compared to peritoneal dialysis in chronic dialysis patients (HR 2.19).
Why the study?
What are the incidence and risk factors for hospitalized atrial fibrillation and mortality in chronic dialysis patients?
Population
3,374 chronic dialysis patients in the United States who started dialysis in 1996
Design
Cohort
Follow-up
From 1996 until November 2000
Authors
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HD patients may need closer AF monitoring; leaves open whether modality independently drives arrhythmia risk.
Cohort (n=3,374)
Yes
What are the incidence and risk factors for hospitalized atrial fibrillation and mortality in chronic dialysis patients?
Hazard Ratio: 2.19 (95% CI 1.17–4.13)
Absolute Event Rate: 4.6% vs 2.8%
p-value: p=0.015
Dialysis patients have a high incidence of atrial fibrillation driven by established risk factors and hemodialysis, while baseline coumadin use is associated with improved survival in those hospitalized for atrial fibrillation.
Abbott et al. (2003) conducted a cohort in End-stage renal disease on chronic dialysis (n=3,374). Hemodialysis vs. Peritoneal dialysis was evaluated on Time to first hospitalization for atrial fibrillation (HR 2.19, 95% CI 1.17-4.13, p=0.015). Hemodialysis was associated with a significantly higher risk of hospitalization for atrial fibrillation compared to peritoneal dialysis in chronic dialysis patients (HR 2.19).
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