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March 1, 1994Proceedings of the National Academy of SciencesOpen Access

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

Bradley R. Cairns Yeon‐Jeong Kim Michael H. Sayre Brehon C. Laurent Roger D. Kornberg

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Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

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Cite This Study

Cairns et al. (1994) studied this question.

synapsesocial.com/papers/6a22306690e08a95395828f2 https://doi.org/10.1073/pnas.91.5.1950

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