A petroleum ether extract of Peperomia galoides showed significant in vitro activity against three Leishmania species and Trypanosoma cruzi. Three major prenylated diphenols, including two known compounds, grifolic acid [1], and grifolin [2], and the new substance piperogalin [3], have been isolated. Structures were established on the basis of spectral analysis including 2D nmr spectroscopy.
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Mahiou et al. (1995) studied this question.