Answers are grounded in this paper and cite their sources.
Nitrite, long considered a biologically inert metabolite of nitric oxide (NO) oxidation, is now accepted as a physiological storage pool of NO that can be reduced to bioactive NO in hypoxic conditions to mediate a spectrum of physiological responses in blood and tissue. This graphical review will provide a broad overview of the role of nitrite in physiology, focusing on its formation and reduction to NO as well as its regulation of the mitochondrion- an emerging subcellular target for its biological actions in tissues.
No takes yet. Share an insight, caveat, or question.
Sruti Shiva (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: