CMOS photodetectors and imaging systems have shown that they possess adequate performance characteristics to replace CCDs or PMTs in some biomedical applications, thereby providing low power, portable, and cheap integrated bioimaging systems. Some advanced solutions, like novel active pixel sensors that detect ultra-low light levels, and avalanche photodiodes that are integrated in CMOS and perform single photon detection, are addressed in this paper.
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Faramarzpour et al. (2008) studied this question.
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