What question did this study set out to answer?

This research aims to assess the association between oral contraceptive use and breast cancer risk, specifically by molecular subtype among young women.

March 14, 2014Cancer Epidemiology Biomarkers & PreventionOpen Access

Oral Contraceptives and Breast Cancer Risk Overall and by Molecular Subtype Among Young Women

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Authors

EBElisabeth F. BeaberDartmouth College KMKathleen E. MaloneCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa MTMei-Tzu C. TangFred Hutch Cancer Center

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Implication

Population-based case-control study examines breast cancer risk linked to oral contraceptive use in young women, suggesting implications for monitoring.

Key Points

This research aims to assess the association between oral contraceptive use and breast cancer risk, specifically by molecular subtype among young women.
Conducted a population-based case-control study in Seattle-Puget Sound area from 2004 to 2010 with 985 breast cancer cases and 882 controls.
Information on contraceptive use and participant characteristics was obtained through in-person interviews.
Multivariable-adjusted logistic regression was applied to calculate odds ratios and confidence intervals.
Lifetime OC use for ≥ 15 years was linked to a 1.5 odds ratio (95% CI, 1.1-2.2) for breast cancer risk.
Current OC use for ≥ 5 years increased risk with an odds ratio of 1.6 (95% CI, 1.1-2.5).
The risk was particularly elevated in women ages 20-39 for estrogen receptor-negative (OR, 3.5; 95% CI, 1.3-9.0) and triple-negative breast cancer (OR, 3.7; 95% CI, 1.2-11.8).

Cite This Study

Beaber et al. (2014) studied this question.

synapsesocial.com/papers/6a223de04ae3d5108797060a https://doi.org/10.1158/1055-9965.epi-13-0944

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Implication

Population-based case-control study examines breast cancer risk linked to oral contraceptive use in young women, suggesting implications for monitoring.

Oral Contraceptives and Breast Cancer Risk Overall and by Molecular Subtype Among Young Women

Discussion

Member takes

Implication

Key Points

Cite This Study

Oral Contraceptives and Breast Cancer Risk Overall and by Molecular Subtype Among Young Women

Discussion

Member takes

Implication

Key Points

Cite This Study

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