Hyponatremia and in Hospital Mortality in Acute St Elevation Myocardial Infarction

The present study is done to determine the prevalence and prognostic implications of hyponatremia in the setting of acute ST-elevation myocardial infarction. The study sample consists of 50 patients presenting with acute ST-elevation myocardial infarction. Plasma sodium concentrations were obtained on admission and at 24, 48, and 72 hours thereafter. Patients with ckd stage 3, 4 and 5, CCF patients on diuretics, previous history of head injury and stroke, known hypothyroidism patients and nephrotic syndrome are excluded in this study. Hyponatremia, defined as a plasma sodium level <135 mmol/L (<135 mEq/L), is present in 20 patients within first 72 hours of hospitalization where 25% patients died. In rest of 30 patients, only 3.3% of patients died. Hyponatremia on admission or early development of hyponatremia in patients with acute STelevation myocardial infarction is an independent predictor of mortality and prognosis.