St Elevation Myocardial Infarction

OBJECTIVE: To evaluate the frequency of hyponatremia and its prognosticimportance in ST elevation myocardial infarction. Period: Six months. Design: Case series.Setting: Tertiary care hospital Hyderabad. Methods: All the cases with ST elevation myocardialinfarction admitted in the CCU were recruited and evaluate for serum sodium level at admissionand then at 24, 48 and 72 hours. The data was analyzed in SPSS 16 and the frequency andpercentage was calculated. Results: One hundred patients with acute myocardial infarctionwere recruited and assessed for sodium level. The mean age ±SD of whole population was57.52±9.51 whereas in male and female population it was 58.72±7.53 and 53.84±7.93respectively. The sodium level was 130.21±3.42 and 127.41±4.21 in male and femalepopulation. The p-value was statistically significant (<0.01) in context to age and sex whereasthe age in context to hyponatremia is non significant (p=0.77). The hyponatremia and itsseverity was statistically significant in context to sex (p=0.04) and duration of the myocardialinfarction (p=0.03). The serum sodium level in context to duration of MI was also significant(p=0.03) whereas the mortality at the end of 30 days was 11% of which 02 patients had normalsodium level while the 09 had low sodium level (hyponatremia). Conclusion: Hyponatremia inpatients with acute STEMI is a important predictor of thirty days mortality.