Key result
Exercise training significantly improved isovolumetric relaxation time (-5.1 msec vs 6.5 msec in controls) and reduced the apnea-hypopnea index in patients with obstructive sleep apnea.
Why the study?
Exercise training is an adjunctive treatment for obstructive sleep apnea, but its effects on heart remodeling in this population are unknown.
Does exercise training improve markers of diastolic function, sleep parameters, and functional capacity in sedentary patients with obstructive sleep apnea?
RCT (n=38)
Single-blind (echocardiography performed by blinded physician)
Randomly assigned on a 1:1 basis
No
Does exercise training improve markers of diastolic function, sleep parameters, and functional capacity in sedentary patients with obstructive sleep apnea?
In sedentary patients with obstructive sleep apnea, a 72-session exercise training program modestly but significantly improved sleep severity, functional capacity, and isovolumetric relaxation time.
Supports exercise training to improve diastolic function and apnea severity in OSA; extends RCT evidence for lifestyle interventions.
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Durante et al. (2022) conducted an RCT in Obstructive sleep apnea (n=38). Exercise training vs. Untrained (sedentary control) was evaluated on Change in isovolumetric relaxation time (IVRT) (p=<0.05). Exercise training significantly improved isovolumetric relaxation time (-5.1 msec vs 6.5 msec in controls) and reduced the apnea-hypopnea index in patients with obstructive sleep apnea.
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