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April 1, 1992Proceedings of the National Academy of SciencesOpen Access

An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals.

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Authors

EAE AbeMaterials Science & EngineeringRMRené de Waal MalefytSynthego (United States)IMIkuo MatsudaHyogo Medical University

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Cite This Study

Abe et al. (1992) studied this question.

synapsesocial.com/papers/6a224c2ee8ef4064f24edecbhttps://doi.org/10.1073/pnas.89.7.2864
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Identification of a Putative Regulator of Early T Cell Activation Genes1988 · 962 citations
  2. 2Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.1989 · 161 citations
  3. 3Characterization of Antigen Receptor Response Elements within the Interleukin-2 Enhancer1988 · 148 citations
  4. 4Inducible and non-inducible factors co-operatively activate the GM-CSF promoter by interacting with adjacent DNA motifs1990 · 31 citations
  5. 5Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production.1991 · 626 citations