The R92Q mutation in cardiac troponin T leads to significant defects in myocardial energetics and contractile reserve in a murine model of familial hypertrophic cardiomyopathy.
No takes yet. Share an insight, caveat, or question.
Myocardial energetic defects may limit contractile reserve in R92Q HCM; leaves open human relevance and therapeutic targeting.
Javadpour et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: