Key result
Surgical aortic valve replacement resulted in a significantly greater reduction in left ventricular mass (17.92%) compared to transcatheter aortic valve implantation (4.28%) at 6 months.
Why the study?
Does transcatheter aortic valve implantation compared to surgical aortic valve replacement improve left ventricular mass regression in patients with severe aortic stenosis?
Observational (n=315)
No
Does transcatheter aortic valve implantation compared to surgical aortic valve replacement improve left ventricular mass regression in patients with severe aortic stenosis?
SAVR provides superior left ventricular mass regression at 6 months compared to TAVI in patients with severe aortic stenosis, though both interventions yield benefits.
Introduction: Severe aortic stenosis is often associated with left ventricular hypertrophy (LVH). Elevated left ventricular mass (LVM) is linked to higher cardiovascular morbidity and mortality. Traditionally, surgical aortic valve replacement (SAVR) has been the standard treatment, but transcatheter aortic valve implantation (TAVI) offers an alternative for high-risk surgical patients. Understanding how these interventions affect left ventricular mass regression is crucial.
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Țăruș et al. (2023) conducted an observational in Severe aortic stenosis (n=315). Transcatheter Aortic Valve Implantation (TAVI) vs. Surgical Aortic Valve Replacement (SAVR) was evaluated on Percentage reduction in left ventricular mass (LVM) at 6 months (Beta -0.21, 95% CI -20.112 to -4.360, p=<0.01). Surgical aortic valve replacement resulted in a significantly greater reduction in left ventricular mass (17.92%) compared to transcatheter aortic valve implantation (4.28%) at 6 months.
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