Bedside right ventricle quantification using 3D echocardiography was feasible in 97.8% of children and showed good agreement with MRI, underestimating RV ejection fraction by 2.1%.
Observational (n=136)
Does bedside 3D transthoracic echocardiography accurately quantify right ventricular volumes and function compared to cardiac MRI in children with congenital heart disease?
Bedside 3D echocardiography is a feasible and accurate non-invasive method for right ventricular quantification in children with congenital heart disease, showing good agreement with cardiac MRI.
• Accurate quantification of the RV is crucial in CHD. • RV quantification from 3D TTE is feasible in children with CHD. • RV quantification from 3D TTE is accurate compared with MRI. • This technique seems appropriate for the daily follow-up of children with CHD. Accurate quantification of right ventricular (RV) volumes and function is crucial for the management of congenital heart diseases. We aimed to assess the feasibility and accuracy of bedside analysis using new RV quantification software from three-dimensional transthoracic echocardiography in children with or without congenital heart disease, and to compare measurements with cardiac magnetic resonance imaging. We included paediatric patients with congenital heart disease (106 patients) responsible for RV volume overload and a control group (30 patients). All patients underwent three-dimensional transthoracic echocardiography using a Vivid E95 ultrasound system. RV end-diastolic and end-systolic volumes and RV ejection fraction were obtained using RV quantification software. Measurements were compared between RV quantification and cardiac magnetic resonance imaging in 27 patients. Bedside RV quantification analysis was feasible in 133 patients (97.8%). Manual contour adjustment was necessary in 126 patients (93%). The mean time of analysis was 62 ± 42 s. RV end-diastolic and end-systolic volumes were larger in the congenital heart disease group than the control group: median 85.0 (interquartile range 29.5) mL/m 2 vs 55.0 (interquartile range 20.5) mL/m 2 for RV end-diastolic volume and 42.5 (interquartile range 15.3) mL/m 2 vs 29.0 (interquartile range 11.8) mL/m 2 for RV end-systolic volume, respectively. Good agreement for RV end-diastolic and end-systolic volumes and RV ejection fraction was found between RV quantification and magnetic resonance imaging measurements. RV quantification software underestimated RV end-diastolic volume/body surface area by 3 mL/m 2 and RV ejection fraction by 2.1%, and overestimated RV end-systolic volume/body surface area by 0.2 mL/m 2 . We found good feasibility and accuracy of bedside RV quantification analysis from three-dimensional transthoracic echocardiography in children with or without congenital heart disease. RV quantification could be a reliable and non-invasive method for RV assessment in daily practice, facilitating appropriate management and follow-up care.
Hadeed et al. (Thu,) conducted a observational in Congenital heart disease (n=136). Three-dimensional transthoracic echocardiography (3D TTE) vs. Cardiac magnetic resonance imaging was evaluated on Feasibility and accuracy of RV quantification compared with cardiac magnetic resonance imaging. Bedside right ventricle quantification using 3D echocardiography was feasible in 97.8% of children and showed good agreement with MRI, underestimating RV ejection fraction by 2.1%.