What question did this study set out to answer?

To investigate the structural organization of the human ornithine-delta-aminotransferase gene and its expression across different tissues.

Human ornithine-delta-aminotransferase. cDNA cloning and analysis of the structural gene.

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Randomized trial reveals ornithine-delta-aminotransferase gene structure in humans, suggesting insights for genetic disorders.

To investigate the structural organization of the human ornithine-delta-aminotransferase gene and its expression across different tissues.
Cloning of near full-length rat and human liver OAT cDNAs
Mapping the human OAT structural gene to chromosome 10
Analyzing the 5'-flanking region and exons of the OAT gene.
The human OAT structural gene is 21 kilobase pairs long and contains 11 exons.
Exon 2 was absent in all studied cDNAs but identified through homology to X-linked processed OAT pseudogenes.
The 5'-flanking region shows characteristics of both housekeeping genes and tissue-specific inducible genes.

Mitchell et al. (1988) studied this question.

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