Mortality associated with anaesthesia: a qualitative analysis to identify risk factors
Key result
Anaesthesia was associated with a 24-hour peri-operative death incidence of 8.8 per 10,000 anaesthetics (95% CI 8.2-9.5), with human failure contributing to 75% of anaesthesia-related deaths.
Population
869,483 patients who underwent either general, regional or combined anaesthesia from 1 January 1995 to 1…
Design
Cohort
Follow-up
24 hours
Authors
Discussion
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Member takes
Implication
Highlights human factors in peri-operative deaths; hypothesis-generating for targeted safety interventions in anaesthesia.
Study Design
Type
Cohort (n=869,483)
Structured PICO
P
Population
869,483 patients who underwent general, regional, or combined anaesthesia between 1995 and 1997, evaluated for 24-hour peri-operative mortality and coma.
E
Exposure
General, regional or combined anaesthesia
O
Outcome
Incidence of 24-h peri-operative death, peri-operative coma, and anaesthesia-related deathhard clinical
Anaesthesia-related mortality occurs in approximately 1.4 per 10,000 cases, with human failure, inadequate patient preparation, and cardiovascular management issues identified as major contributing risk factors.
Cite This Study
Arbous et al. (2001) conducted a cohort in Patients undergoing anaesthesia (n=869,483). Anaesthesia (general, regional, or combined) was evaluated on 24-h peri-operative death per 10,000 anaesthetics (95% CI 8.2-9.5). Anaesthesia was associated with a 24-hour peri-operative death incidence of 8.8 per 10,000 anaesthetics (95% CI 8.2-9.5), with human failure contributing to 75% of anaesthesia-related deaths.