Key result
Surgical revascularization and ventricular geometry optimization in patients with severe left ventricular dysfunction improved quality of life and NYHA class, with 5 early and 3 late deaths.
Why the study?
Does surgical revascularization combined with ventricular remodelling or mitral annuloplasty improve clinical and functional outcomes in patients with severe left ventricular dysfunction?
Population
53 patients with severe, global impairment of left ventricular function without discrete aneurysm formation…
Design
Cohort
Follow-up
mean 22-26 months
Authors
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May support evaluation in select transplant-referred patients; leaves open need for randomized trials to confirm net benefit.
Cohort (n=53)
Does surgical revascularization combined with ventricular remodelling or mitral annuloplasty improve clinical and functional outcomes in patients with severe left ventricular dysfunction?
Surgical revascularization combined with ventricular remodeling or mitral annuloplasty can improve quality of life and ejection fraction in highly selected patients with severe LV dysfunction who might otherwise be referred for transplantation.
V. Pathi (1998) conducted a cohort in Severe left ventricular dysfunction (n=53). Surgical revascularization with mitral annuloplasty and/or free wall remodelling was evaluated on Quality of life, NYHA functional class, ejection fraction, and mortality. Surgical revascularization and ventricular geometry optimization in patients with severe left ventricular dysfunction improved quality of life and NYHA class, with 5 early and 3 late deaths.
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