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November 1, 2014Psychosomatic Medicine

Post–Myocardial Infarction Anxiety or Depressive Symptoms and Risk of New Cardiovascular Events or Death

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Why the study?

Are anxiety or depressive symptoms 3 months post-MI independently associated with new cardiovascular events or death?

Population

896 persons with first-time myocardial infarction (MI) between 1 January 2009 and 31 December 2009

Design

Cohort

Follow-up

1975 person-years (followed up until 31 July 2012)

Authors

KLKaren Kjær LarsenCopenhagen University HospitalBCBo ChristensenAarhus UniversityTNTine Jepsen NielsenAarhus University

Discussion

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Implication

Anxiety symptoms should not yet inform post-MI risk stratification; leaves open whether depression-targeted interventions affect mortality.

Structured PICO

Are anxiety or depressive symptoms 3 months post-MI independently associated with new cardiovascular events or death?

P
Population
896 persons with first-time myocardial infarction (MI) between 1 January 2009 and 31 December 2009
I
Intervention
Anxiety or depressive symptoms 3 months after MI (assessed via Hospital Anxiety and Depression Scale)
O
Outcome
New cardiovascular events and deathhard clinical

Post-MI anxiety symptoms are not an independent prognostic risk factor for new cardiovascular events or death, whereas depressive symptoms are independently associated with increased mortality.

Cite This Study

Larsen et al. (2014) studied this question.

synapsesocial.com/papers/6a2263d2ff4932f4f390fcabhttps://doi.org/10.1097/psy.0000000000000115

Topics

Women and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Low Heart Rate Variability and the Effect of Depression on Post–Myocardial Infarction Mortality2005 · 259 citations
  2. 2Personality and Mortality After Myocardial Infarction1995 · 314 citations
  3. 3The Hospital Anxiety and Depression Scale1983 · 47,410 citations
  4. 4Prognostic Association of Anxiety Post Myocardial Infarction With Mortality and New Cardiac Events: A Meta-Analysis2010 · 391 citations
  5. 5Comparing symptoms of depression and anxiety as predictors of cardiac events and increased health care consumption after myocardial infarction2003 · 360 citations