Key result
Blood deficiency pattern (OR 2.269, P=0.017) and Qi stagnation pattern (OR 1.999, P=0.041) were independently associated with diabetic nephropathy in patients with T2DM and chronic kidney disease.
Why the study?
The study was conducted to evaluate clinical characteristics related to the differential diagnosis of diabetic nephropathy and non-diabetic renal disease.
Do Traditional Chinese Medicine symptom patterns help differentiate diabetic nephropathy from non-diabetic renal disease in patients with T2DM and CKD?
Observational
Do Traditional Chinese Medicine symptom patterns help differentiate diabetic nephropathy from non-diabetic renal disease in patients with T2DM and CKD?
Odds Ratio: 2.269
p-value: p=0.017
Traditional Chinese Medicine symptom patterns, specifically blood deficiency and Qi stagnation, may aid in the noninvasive differential diagnosis of diabetic nephropathy versus non-diabetic renal disease.
May aid noninvasive DN differentiation in T2DM-CKD; leaves open prospective validation before clinical use.
OBJECTIVE: To study the clinical characteristics relating to differential diagnosis of diabetic nephropathy (DN) and non-diabetic renal disease (NDRD). METHODS: The subjects were patients with type 2 diabetes mellitus (T2DM) complicated with chronic kidney disease (CKD). Western medical history data and Traditional Chinese Medicine (TCM) symptom pattern were collected, and logistic regression was used to analyze. RESULTS: Blood deficiency pattern [odds ratio (OR) = 2.269, P = 0.017] and Qi stagnation pattern (OR = 1.999, P = 0.041) are independently related to DN. CONCLUSIONS: TCM factors blood deficiency pattern and Qi stagnation pattern are relating to differential diagnosis of DN and NDRD.
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Yilun et al. (2023) conducted an observational in Type 2 diabetes mellitus (T2DM) complicated with chronic kidney disease (CKD). Traditional Chinese Medicine (TCM) symptom patterns (Blood deficiency and Qi stagnation) was evaluated on Diabetic nephropathy (DN) (OR 2.269, p=0.017). Blood deficiency pattern (OR 2.269, P=0.017) and Qi stagnation pattern (OR 1.999, P=0.041) were independently associated with diabetic nephropathy in patients with T2DM and chronic kidney disease.
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