Key result
Large-bore catheters enable rapid thrombus removal without lytic agents in acute PE.
Why the study?
Pulmonary embolism causes substantial cardiovascular mortality and long-term morbidity, and several large-bore catheter devices are approved for rapid thrombus removal without lytic agents.
Large-bore catheter devices offer an interventional option for expeditious thrombus removal without lytic agents in patients with acute high-risk pulmonary embolism.
Answers are grounded in this paper and cite their sources.
May offer lytic-free removal for high-risk PE; leaves open need for RCTs before practice change.
Pulmonary embolism (PE) is one of the leading causes of cardiovascular mortality in the United States. Even in those patients who get treatment in the acute phase, they are at risk of developing pulmonary hypertension, recurrent PE, which can lead to functional impairment and decreased survival. Interventional therapies for PE are reserved for unstable patients with high-risk PE or stable patients at high risk for decompensation. Several large-bore devices are currently approved for the treatment of PE and can provide expeditious thrombus removal without the need for lytic agents. Here, we review some of the large-bore catheter devices available for the treatment of acute PE.
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Katuwal et al. (2026) conducted a review in Pulmonary embolism. Large-bore catheter devices was evaluated. Large-bore catheter devices can provide expeditious thrombus removal without the need for lytic agents in the treatment of acute pulmonary embolism.
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