SUPPORT+ digital self-management and clinical support for advanced cancer: A randomized controlled trial.

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Key Points

This study aims to evaluate the effectiveness of the SUPPORT+ mobile app in improving quality of life and reducing emergency visits for advanced cancer patients.
Conducted as a multi-centre randomized controlled trial across 6 clinics in Hong Kong from Jan 2023 to Feb 2025.
633 patients with advanced cancers not receiving systemic treatment were randomized to SUPPORT+ or usual care for 18 weeks.
Primary outcome measured was change in health-related quality of life using the EQ-5D-5L scale.
HRQoL was better maintained in the SUPPORT+ group (mean difference −0.18; p<0.001) compared to usual care.
Fewer patients in the SUPPORT+ group experienced deterioration in ECOG PS (12.4% vs. 18.9%; p=0.016).
Hospitalization outcomes favored SUPPORT+, with significant reductions in admissions and shorter lengths of stay (both p≤0.001).

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Randomized trial demonstrates improved quality of life and reduced hospitalizations in advanced cancer patients using digital support.

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Chan et al. (2026) studied this question.

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