When Posterior Reversible Encephalopathy Syndrome is Not Posterior: An Atypical Pediatric Presentation

A bstract Posterior reversible encephalopathy syndrome (PRES) is a distinct clinico-radiological entity observed especially in cases of renal disorders, hypertension, immunosuppressive agent use, and malignancy. We describe an adolescent girl with lupus nephritis who presented with atypical neuroimaging of PRES. She improved with blood pressure control and anti-seizure medication. This case highlights atypical radiological features of PRES in autoimmune and renal disease, emphasizing early recognition and prompt management to prevent irreversible neurological injury.