Uterine Fibroids and Infertility

The present study, in the form of a literature review, aims to investigate the association between uterine fibroids and infertility. Uterine fibroids represent one of the most common benign tumors of the female reproductive system and are frequently diagnosed in women of reproductive age. It is estimated that fibroids are the primary cause of infertility in approximately 2–3% of women experiencing difficulty conceiving. Myomas, depending on their location in the uterus, have been associated with recurrent pregnancy loss and infertility. Submucosal fibroids have been strongly associated with reduced conception rates, recurrent pregnancy loss, and overall poorer reproductive outcomes. Resection of these fibroids has been clearly shown to increase pregnancy rates. Subserosal, on the other hand, have no effect on fertility results and is not beneficial to remove. Intramural fibroids seem to impair fertility, although literature is not concise and there is no clear consensus regarding their management.