Why the study?
Management of CTO in diabetics is challenging, with a trend toward early revascularization instead of OMT, prompting an evaluation of whether early revascularization improves outcomes.
Does early revascularization improve morbidity and mortality outcomes compared to optimal medical therapy in diabetic patients with chronic total occlusions?
Does early revascularization improve morbidity and mortality outcomes compared to optimal medical therapy in diabetic patients with chronic total occlusions?
This meta-analysis evaluates early revascularization versus optimal medical therapy in diabetic patients with chronic total occlusions, though specific results are missing from the abstract.
Answers are grounded in this paper and cite their sources.
Evidence on early revascularization versus OMT in diabetic CTOs remains inconclusive; leaves open optimal strategy.
BACKGROUND: Management of chronic total occlusions (CTO) in diabetics is challenging, with a recent trend towards early revascularization [ER: Percutaneous coronary intervention (PCI) and bypass grafting] instead of optimal medical therapy (OMT). We hypothesize that ER improves morbidity and mortality outcomes in diabetic patients with CTOs as compared to OMT. AIM: To determine the long term clinical outcomes and to compare morbidity and mortality between OMT and ER in diabetic patients with CTOs. METHODS: value < 0.05. Primary outcome of interest was all-cause death. Secondary outcomes included cardiac death, prompt revascularization (ER) or repeat myocardial infarction (MI). Due to scarcity of data, both Randomized control trials and observational studies were included. 4 eligible articles, containing 2248 patients were identified (1252 in OMT and 1196 in ER). Mean follow-up was 45-60 mo. CONCLUSION: PCI.
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Khan et al. (2020) studied this question.
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